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Glacios 2
TEM ActiveThermo Fisher Scientific — Glacios 2
Cryo-TEM with cold FEG and direct electron detector for cryo-tomography applications.
Voltage 200 kV
Gun E-CFEG
Monochromator N/A
Pole-piece C-twin (11 mm)
Feature Phase Plate Solution
Camera TFS Falcon4i DED
Accessory Sample Autoloader
Software Tomo Live
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Overview
The Thermo Fisher Scientific Glacios 2 is a dedicated cryo-TEM equipped with an E-CFEG (enhanced cold field-emission gun) and a Falcon4i direct electron detector. With a wide-gap C-twin pole piece (11 mm) and sample autoloader, it is optimized for automated cryo-tomography workflows including single-particle analysis and cellular tomography.
Key Features
- E-CFEG electron source: Cold FEG delivering high coherence and narrow energy spread for superior phase contrast
- Falcon4i direct electron detector (DED): High-DQE counting-mode detector for dose-efficient cryo-imaging
- Phase Plate Solution: Enhanced contrast for unstained biological specimens and beam-sensitive materials
- Sample Autoloader: Automated multi-grid loading for high-throughput data collection
- Tomo Live software: Streamlined cryo-tomography acquisition and real-time reconstruction
Applications
- Cryo-electron tomography of cells and organelles
- Single-particle cryo-EM data collection
- Cryo-imaging of beam-sensitive energy materials
- Phase-contrast imaging of low-Z materials and biological specimens